Presqu'ile, or Presqui'ile, (pronounced Preesk-eel), the French term for "peninsula", was an appropriate name for the house built in Hampstead Village at 2 Amherst St., Charleston, South Carolina between 1802 and 1808 because, at the time, the house stood on a finger of high ground that projected into the marshes of the Cooper River.

A square, three-story rear wing in the Greek Revival style was added by Henry Grimke, a planter who acquired the house in 1840.

Subsequent owners of the home have included Theodore S. Marion, Joshua T. Ward, Maj. Samuel Porcher (the likely builder of Numertia Plantation), Henry Grimke, Joseph Leary, C.F.

Presqu’ile received Carolopolis Awards in 1967 and 1978 from the Preservation Society of Charleston and was listed on the National Register of Historic Places in 1978.

This article about a property in Charleston County, South Carolina on the National Register of Historic Places is a stub.