[1][2] The hospital had its origins in a House of Recovery constructed between 1829 and 1833.

[1] It was extended by James Hibbert between 1866 and 1870[3] to create the Preston and County of Lancaster Royal Infirmary; this facility became the Preston and County of Lancaster Queen Victoria Royal Infirmary in 1929.

[4] A further two storeys were added to the main block in 1936.

[1] It joined the National Health Service as the Preston Royal Infirmary in 1948 and, after services had transferred to the Royal Preston Hospital, it closed in 1990.

[4] Two buildings each gained Grade II listed building status on 7 April 1988, and were subsequently converted for use as student halls of residence.