were eliminated from making the Liguilla with a 3-2 loss to Monterrey and thus could not defend their title, and Veracruz was relegated to the Primera División A after finishing last on the percentage table.
Four teams advanced to what is known as the Repechaje (playoff qualifiers), and these are being San Luis, Pachuca, Necaxa, and Atlas.
On June 1, 2008 Santos Laguna beat Cruz Azul on 3-2 aggregate to win the Clausura 2008 trophy.
By winning Clausura 2008, Santos earned a berth in the 2008–09 CONCACAF Champions League Group Stage.
By being the Clausura 2008 runner-up, Cruz Azul earned a berth in the 2008–09 CONCACAF Champions League Preliminary Round.