[4] Gyasi started taking pictures in 2011 and bought his first iPhone in 2014 which was his primary tool he uses in creating his art pieces at the time.
[5] He began with snapshots of friends, family and models from his hometown of Ghana and then realized he could seriously use his phone as an arts creation tool, as a means of expression.
[8] Prince art practice over the years has gotten him to be comfortable with every medium he chooses to use to express himself[9] with which has gotten him recognized as Time's Next Generation Leader in visual artistry.
[20] In this project he shot Ghanaian hiplife musicians like Gyedu-Blay Ambolley, Reggie Rockstone, Okyeame Kwame, Rab Bakari, Abrewa Nana, Hammer of The Last Two, Beat Menace, Gurunkz, Joey B, EL (rapper), DJ Breezy, Stargo, Kirani Ayat, Akan (Musician), Kiddblack, Ansah Live, Imani N.A.D, Toyboi, Kwesi Arthur and Shadow.
He performed alongside Virgil Abloh’s new creative cast; Milanese choreographer, Michele Rizzo and Japanese DJ, Kiri Okuyama, all rocking apparel from the brands new line.
[25] In 26 March 2021, Prince got commissioned by Madame Figaro France to shoot Naomi Campbell for the cover image of that issue.
[33] In this issue Prince shot the following people for The Cal, they are Otumfuo Nana Osei Tutu II, Naomi Campbell, Margot Lee Shetterly, Angela Bassett, Amanda Gorman, Tiwa Savage, Idris Elba, Jeymes Samuel, Amoako Boafo, Teyana Taylor and Marcel Desailly.
[34][35] In January 2024, Prince collaborated with Balmain's creative director Olivier Rousteing to reproduce his images on garments and turn them into clothes.
Prince Gyasi was invited on 9 April 2019 to give a speech about his creative works during the 2019 Skoll World Forum at the Oxford University in London.