[12] On 16 August 1989 at Bucharest, Radu Duda married Viorica Tanta Begnescu; this marriage was dissolved by divorce on 12 November 1992.

[13] In 1996 (24 July, civilly; 21 September, religiously), he married Princess Margareta, eldest daughter of King Michael I of Romania and Queen Anne.

As spouse of Princess Margareta, Radu often accompanies his wife, sometimes solo, to support social projects and promote the Romanian economy.

Radu graduated from the Costache Negruzzi High School in Iași in 1979, and from the University of Drama and Film in Bucharest in 1984, and had over twenty years of artistic activity in Romania as well as in other European countries, the Americas, Asia, and Africa.

In August 2004 he participated in the two-week Program for Senior Executives in National and International Security at the John F. Kennedy School of Government at Harvard University.

Prince Radu's lectures address topics related to Romania's integration into the Euro-Atlantic structures, defense, and security, geopolitics and diplomacy, culture, economics, and education.

Prince Radu currently serves on the Board of Advisors to the Global Panel Foundation, an NGO that works behind the scenes in crisis areas around the world.

In an official communique sent to the newspaper,[42] Radu denied any such lobbying activities, stating that as patron of the British-Romanian Chamber of Commerce in which BAE Systems is a member, he met with this as well as other British companies' representatives.

Radu has been the target of press attacks[43] for having been an informer for Communist Romania's dreaded[44][45][46][47] Securitate, the secret police, during Nicolae Ceaușescu's dictatorship.

Căminul românesc magazine from Geneva[48][49] published an article by Nicolette (Nicoleta) Franck, a journalist close to King Michael, about whom she wrote many books.

In an article published by the Adevărul daily, Radu denied allegations of his supposed involvement with the Securitate: "I have not collaborated with the Securitate…in 1986 there was an attempt to recruit me.

Wealthy Romanians in exile, who have been surveyed by the communist era political police Securitate even in subway stations, considered the compromise as intolerable."

[58] Karl Friedrich also warned Radu that the Hohenzollern family would take "legal measures" in case these things were to happen again and demanded that he cease to use the title of "Prince of Hohenzollern-Veringen".

[63][64] The former president of Romania Traian Băsescu does not appreciate Prince Radu[65] and thinks he is detrimental to the Romanians' public perception of the idea of monarchy.

In a 2004 poll conducted by the PSD,[69] of whose coalition government he was at that time the Special Representative, Prince Radu scored just 3.4% as a potential candidate in the upcoming Romanian presidential elections.

[74] In the presence of Princess Margareta, Prince Radu announced his candidacy for the Romanian Presidency in a press conference at the Elisabeta Palace in Bucharest, Romania, on 9 April 2009.