Prince of Wales was an East Indiaman launched in 1803.

Captain John Price left the Downs on 9 May 1803, bound for Bombay and Madras.

Because she was sailing in a time of war, Price took out a letter of marque, which he received on 2 July 1803.

[1] In June Prince of Wales travelled from St Helena in convoy with the East Indiamen City of London, Ceylon, Calcutta, and Wyndham, two vessels from the South Seas, Lively and Vulture, and Rolla, which had transported convicts to New South Wales.

[5] On the way the convoy ran into severe weather with the result that Prince of Wales foundered with the loss of all on board.