Princess Margaretha of Saxony, Duchess of Saxony (German: Prinzessin Margaretha Karoline Friederike Cecilie Auguste Amalie Josephine Elisabeth Maria Johanna von Sachsen, Herzogin zu Sachsen; 24 May 1840 – 15 September 1858[1]) was the eighth child and fifth eldest daughter of King John of Saxony and his wife Princess Amalie Auguste of Bavaria and a younger sister of Kings Albert of Saxony and George of Saxony.

Through her marriage to Archduke Charles Louis of Austria, Margaretha was a member of the House of Habsburg-Lorraine and an Archduchess and Princess of Austria and Princess of Hungary, Croatia, Bohemia, and Tuscany.

[2] Margaretha married her first cousin Archduke Charles Louis of Austria, third eldest son of Archduke Franz Karl of Austria and his wife, Princess Sophie of Bavaria, on 4 November 1856 in Dresden.

[2][1] The marriage was happy, but only lasted two years and remained childless.

On a trip to Italy, Margaretha contracted typhoid.