They lived, worked, and traveled with the Apostle Paul, who described them as his "fellow workers in Christ Jesus" (Romans 16:3).

Together, they are credited with instructing Apollos, a major evangelist of the first century, and "[explaining] to him the way of God more accurately" (Acts 18:26).

[5] Priscilla and Aquila had been among the Jews expelled from Rome by the Roman Emperor Claudius in the year 49 as written by Suetonius.

Then the couple started out to accompany Paul when he proceeded to Syria, but stopped at Ephesus in the Roman province of Asia, now part of modern Turkey.

In 1 Corinthians 16:19, Paul passes on the greetings of Priscilla and Aquila to their friends in Corinth, indicating that the couple were in his company.

Although acclaimed for its artistry, originality, and literary excellence, it is one of the few books in the New Testament with author anonymity (along with the Gospels and Acts).

The fact that she is always mentioned with her husband, Aquila, disambiguates her from different women revered as saints in Catholicism, Orthodoxy and Lutheranism, such as (1) Priscilla of the Roman Glabrio family, the wife of Quintus Cornelius Pudens, who according to some traditions hosted St. Peter circa AD 42, and (2) a third-century virgin martyr named Priscilla and also called Prisca.

According to church tradition, Aquila did not dwell long in Rome: the Apostle Paul is said to have made him a bishop in Asia Minor.

In Acts 18:24–28, Luke reports the couple explaining Jesus' baptism to Apollos, an important Jewish-Christian evangelist in Ephesus.

Opponents of female pastorship cite his reference to Adam and Eve to be indicating that the issue is a matter of universal gender propriety.

Priscilla instructed the learned Apollos, Lois and Eunice taught Timothy, and Phoebe is named as an overseer and a deacon in the church at Cenchrea.

And all things are from God" and his affirmation of Priscilla's instruction of the prominent evangelist Apollos as evidence that Paul was acceding to the law and customs of his day.