In 1982, Edu-Ware released a second version of the game entitled Prisoner 2, with color and improved high-resolution graphics replacing the original's top-down perspective with a first-person view.

Prisoner 2 was essentially the same as the first Prisoner game, only with updated graphics and a limited number of design changes, several of which referenced other games: Jeff Rovin for Videogaming Illustrated said that "A great piece of computergaming from both a design point of view and as a challenge, though the lack of originality is disappointing.

Thorns for ANALOG Computing said that "Prisoner II is a superb package (I dare not call it a "game") that should provide weeks of entertainment.

Surely among the more complex computer games, it will repay the involved player with hours of enjoyment in a variety of imaginative, challenging, often humorous scenarios.

"[4] Paula Polley for Atari Connection wrote that "Eduware [sic] employees report that the CIA uses Prisoner 2 both to interview applicants and train budding spies in terrorist handling techniques" and also claimed that the game had "been used in the psychiatric field to treat patients suffering from paranoia.