Prisoners of the Ghostland is a 2021 American horror Western film directed by Sion Sono, from a script by Aaron Hendry and Reza Sixo Safai.

Its plot revolves around a notorious criminal, Hero (Nicolas Cage), who is sent to rescue the governor's adopted granddaughter, who has disappeared into a dark region called Ghostland.

In a region of Japan devastated and quarantined years ago following an accident in which highly volatile nuclear waste was spilled after a crash between the waste transport and a prison bus, a settlement called Samurai Town is ruled by an unscrupulous Governor who has blended elements of Japanese society (both modern-day and pre-modern) and the old American West together at his whim, and is keeping a harem of adopted "granddaughters" as his sex slaves.

Having had a revelation during his unconsciousness about his accidental role in the cataclysm, Hero stirs the Ghostlanders into a revolt against the Governor, aided by Psycho and the mutants, his fellow convicts from the fateful accident.

[5][6] In February 2019, shortly after Imogen Poots was cast in a starring role,[7][8] Sono underwent emergency surgery following a heart attack, halting pre-production on the film.

[9] In November 2019, Sofia Boutella, Ed Skrein, Bill Moseley, Young Dais, and Tak Sakaguchi joined the cast, in undisclosed roles, from a script by Aaron Hendry and Reza Sixo Safai.

The website's critics' consensus reads, "Prisoners of the Ghostland is far from Sono's most distinctive work, but viewers in the mood for a deliriously gonzo genre mash-up featuring an explosive performance from Nicolas Cage just might have a ball.

[17] Nick Allen at RogerEbert.com gave the film two out of four stars: "No movie with Nicolas Cage, directed by the wonderfully weird Japanese director Sion Sono, should be this taxing, drawn out, and plainly boring.