[1] HP ProLiant systems led the x86 server market in terms of units and revenue during first quarter of 2010.

Starting August 28, 2014, HP ProLiant Gen9 series were available based on Intel Haswell chipset and DDR4 memory.

[9] In April 2021, HPE introduced the ProLiant Gen10 Plus line of servers, which are built on third-generation Intel Xeon scalable processors.

Equipped with PCIe Gen4 capabilities, the HPE ProLiant DGen10 Plus servers offer improved data transfer rates and higher networking speeds.

ProLiant servers are separated into several different product lines - ML, DL, RL, SL, BL, SY, XL (Apollo), and MicroServer - which generally denote form factor.

The ProLiant ML line comprises tower-based servers (convertible to rack mount) with capacity for internal expansion of disks and interconnects, while the DL line comprises general-purpose rack mount servers.

The RL line compromises cloud-native servers that can handle cloud-native workloads, and the SL line compromises of rack mounted servers designed for use in data centers and environments where high computing power is required.

[10] ProLiant servers made by Compaq were offered with the company's own SmartStart and Insight Management Agents, among other utilities.

[11] Designed to support 50 to 300 virtual machines, the HP ConvergedSystem 300 is configured with ProLiant servers.

[13] HP also provide drivers a software for managing servers such as Management Component Pack which includes hp online configuration utility (hponcfg), Agentless Management Service amsd, Smart Storage Administrator (SSA) ssa, Smart Storage Administrator (SSA) CLI ssacli and Smart Storage Administrator Diagnostic Utility (SSADU) CLI ssaducli.

Blade systems aim towards maximum density and manageability at limited rack space.

The HPE ProLiant MicroServer line of products are entry-level, low power, compact, and affordable servers meant for small business, home office, or edge computing.

There is the option to purchase the server with ClearOS installed in order for users to be able to enable applications via an easy-to-use web-GUI with minimal effort.