Professorville is a registered historic district in Palo Alto, California containing homes that were built by Stanford University professors.

[3] The Professorville Historic District reflects the area's origins and its early years related to the founding of both Stanford University and Palo Alto itself.

[5] The buildings most representative of Professorville are brown-shingled houses with gambrel roofs, whose stylistic influences range from Colonial Revival to American Craftsman.

One of the largest residences, a 3-story, 14-room frame house at 450 Kingsley Avenue, is the former home of Stanford's first physics professor, Fernando Sanford,[6] designed by architect Frank McMurray of Chicago.

The house includes features fashionable at the time, such as a Queen Anne corner tower and a Palladian window in front.