Profluralin is a dinitroaniline herbicide used preëmergently to control annual grasses and broadleaf weeds, in cotton, soybeans, peanuts, sunflower, cabbage, cauliflower, tomato and others.

Profluralin is adsorbed into plantmatter, so there is potential that it stay in crops after harvest.

If applied in high doses to rats, they may exhibit ataxia, slower breathing, salivation, prostration, hyperactivity or dyspnea.

[4] It was sold under the tradenames "Pregard" and "Tolban" (Syngenta),[3] registered in August 1975 and expiring in April 1984.

[7] Profluralin's mode of action is by binding to tubulin microtubules as they form, blocking further growth.