[1] Progress M-54 was launched by a Soyuz-U carrier rocket from Site 1/5 at the Baikonur Cosmodrome.

[1] The spacecraft docked with the aft port of the Zvezda module at 14:42:03 UTC on 10 September 2005.

[2][3] It remained docked for 175 days before undocking at 10:06:10 UTC on 3 March 2006.

[2][5] Progress M-54 carried supplies to the International Space Station, including food, water and oxygen for the crew and equipment for conducting scientific research.

It also carried the radio transmitter for the RadioSkaf satellite, which was assembled aboard the ISS using a retired Orlan spacesuit.