Its mission is the conservation of flora, fauna and priority ecosystems of northeastern Mexico by promoting society's development in harmony with nature.
Pronatura Noreste's projects are based on an ecoregional focus, expanding over the territorial limits determined by states and countries, with special attention on priority sites and the most fragile habitats, species and biodiversity.
Its four ecoregional programs are: The environmental organization currently has conservation projects in the states of Tamaulipas, Nuevo León, Coahuila, Chihuahua and San Luis Potosí.
In 2006, it purchased Cueva de la Boca, a cave near Monterrey that is home to a large population of Mexican free-tailed bats.
Pronatura Noreste's projects receives financial funding from organizations such as CONABIO, the Dallas Zoo, the Environmental Defense Fund, Ford Motor Company, Fondo Mexicano para la Conservación de la Naturaleza, General Motors, the William and Flora Hewlett Foundation, the World Wide Fund for Nature, The Nature Conservancy, Treviño Elizondo A.B.P., the United States Agency for International Development and the United States Fish and Wildlife Service, as well as some Mexican corporate industrial groups, such as CEMEX and ALFA.