[3]: 47–51 Architects and firms represented include Boston's Peabody and Stearns and R. Clipston Sturgis; New York's Grosvenor Atterbury, Donn Barber, J.C. Cady & Co., George S. Chappell, Delano & Aldrich, Ewing & Chappell, James Gamble Rogers, Rossiter & Muller, and Heathcote Woolsey; Philadelphia's Mantle Fielding; Connecticut's Henry Austin and numerous others.

[3]: 51–52 Selected contributing properties in the district are: Non-contributing properties include: In 2002, application was made for a building that was located at 285 Prospect Street to be moved to 380 Edwards Street, while retaining its contributing building status.

The district borders are drawn irregularly to exclude modern construction, and also to exclude properties fronting Whitney Avenue,[3] which are included in the Whitney Avenue Historic District.

It excludes the entire area of the Hillhouse Avenue Historic District, an area that was originally residential, and now is mostly Yale University-owned, and which included within the official neighborhood planning maps for Prospect Hill.

Among other exclusions, the district excludes Yale University's relatively modern buildings on Science Hill.