The historic city centre is well preserved and is protected by law as an urban monument zone.

The western tip of the municipal territory extends into the Drahany Highlands and includes the highest point of Prostějov at 368 m (1,207 ft) above sea level.

The city is situated at the confluence of the Romže River and Hloučela Stream, which is located in Vrahovice.

In 1495, the Plumov estate with Prostějov was bought by the Pernštejn family and the construction of the town walls began.

[4] The Prostějov Castle was built in 1522–1526 by Jan of Pernštejn as a part of town walls.

In the late 19th century, Prostějov was the third largest city in Moravia after Brno and Jihlava.

[8] Oděvní podnik Prostějov, the biggest textile company in the country with about 10,000 employees, was founded in 1964.

After the fall of communism in Czechoslovakia, the company failed to restructure and adapt to market mechanisms, and went bankrupt in 2010.

SK Prostějov, which plays in Czech National Football League (2nd tier), and to the ice hockey club LHK Jestřábi Prostějov, which plays in the 1st Czech Republic Hockey League (2nd tier).

The central square is lined by burgher houses with Renaissance or Baroque cores, and facades mostly from the 19th and 20th centuries.

The landmark of the square is the city hall from 1911–1914 with a 66 metres (217 ft) high tower, which is open to the public.

[12] The Church of the Exaltation of the Holy Cross, founded together with an Augustinian monastery in 1391, is the oldest monument in Prostějov.

It is decorated with frescoes by Jano Köhler and with the Way of the Cross cycle by František Bílek.

[13] The Church of Saint John of Nepomuk, built in 1750–1755, is a part of the former monastery of the Merciful Brothers.