In the Middle Ages, Prusac was part of the Uskoplje area, including the fortresses of Susid and Vesela Straža.

"Bio" means 'white' in the Ikavian accent of Shtokavian dialect, and refers to the white limestone found in this region.

The fortress was enclosed with walls thick two and a half meters in some places, featuring loopholes and cannon holes.

The one side of the fortress allowing access features a six meters wide ditch, with a drawbridge leading to the entrance gate.

The Handanija Mosque is located in the center of Prusac is an exemplary representation of the Bosnia-Herzegovinian Islamic heritage, featuring authentic 17th century architecture.