After his father's death in 1309, Przemko II succeeded him in all his lands with his brothers as co-rulers; however, because he was a child at that time, he moved with his mother Matilda to her dower, Glogów.
Przemko II, along with older brothers Henry IV the Faithful and Jan received Żagań, Ścinawa and Poznań as co-rulers.
In 1318, his mother Matilda died, and Przemko II, with his older brother Henry IV inherited Glogów (since 1317, Jan was an independent Duke of Ścinawa).
This time was particularly difficult for the Duke of Glogów, specially after 1329, when he was the only of Henry III's sons who refused to paid tribute to the Bohemian King.
Przemko II's widow Constance received the city of Glogów as her dower and, according to the treaty of 1326, his brother Henry IV and Jan divided between them the rest of his lands.