It is endemic to Veracruz, Mexico, and known from Cerro Chicahuaxtla (1,300–1,600 m (4,300–5,200 ft) asl)) in Cuatlalpan (the type locality, near Fortín de las Flores) and from Volcán San Martín at elevations of 1,200–1,300 m (3,900–4,300 ft).

These separate populations likely represent distinct species.

[1][3][4][5] Pseudoeurycea nigromaculata is a medium-sized plethodontid: females in the type series (collected by Hobart Muir Smith) measure 51–57 mm (2.0–2.2 in) in snout–vent length.

The body is blackish (lighter in younger specimens), the tail has lighter coloration, and both carry black spots[2] that have given the species its name.

[4] Pseudoeurycea nigromaculata is an arboreal species living in bromeliads in cloud forest.