Pseudothelphusidae is a family of freshwater crabs found chiefly in mountain streams in the Neotropics.

[2] They are believed to have originated in the Greater Antilles and then crossed to Central America via a Pliocene land bridge.

Pseudothelpshusids are of significance to humans because many species are secondary hosts for lung flukes of the genus Paragonimus.

[3] Predators of pseuthelphusid crabs include the yellow-spotted river turtle and the tufted capuchin.

[3] Forty genera are recognised:[4]