Pterotrigonia is an extinct genus of saltwater clams, marine bivalve molluscs in the family Megatrigoniidae.

Species in this genus were facultatively mobile infaunal suspension feeders.

The type species of the genus is Pterotrigonia cristata.

Pterotrigonia thoracica was selected as the state fossil of Tennessee in 1998.

[3][4] Fossils of species within this genus have been found in the Jurassic of Antarctica, Chile and India, as well as in the Cretaceous of Angola, Antarctica, Argentina, Austria, Bulgaria, Chile, Colombia, Cuba, Ecuador, Egypt, France, Hungary, Italy, Japan, Libya, Madagascar, Mexico, Mozambique, New Zealand, Oman, Peru, Portugal, Serbia and Montenegro, South Africa, Spain, Trinidad and Tobago, Russia, Ukraine, United Arab Emirates, United Kingdom, United States and Yemen.