Panama became a part of the Great Colombia after receiving its independence from Spain on November 28, 1821.
The United States helped in this separation process as they had a vested interest in building the Panama Canal.
November 10 is the Cry of Independence (from Spain) which is mainly celebrated in La Villa de Los Santos.
Expect a lot of movement to the countryside, especially on the 3, 4 and 5 of November when most hotels get full.
Tourism on the 10 and 28 depends on the holiday being on a Monday or Friday, making it a long weekend.