Puerto Leguízamo[2] (Spanish pronunciation: [ˈpweɾto leɣiˈsamo]) is a town and municipality located in the Putumayo Department, a southern border region of the Republic of Colombia.

Its Catedral Nuestra Señora del Carmen, dedicated to Our Lady of Mount Carmel, is the cathedral episcopal see of the Latin Catholic missionary pre-diocesan Apostolic Vicariate of Puerto Leguízamo-Solano.

Puerto Leguízamo is served by Caucayá Airport.

Located just a few kilometres south of the equator, Puerto Leguízamo has a tropical rainforest climate (Af) with heavy to very heavy rainfall year-round.

This Department of Putumayo location article is a stub.