This is a list of notable Puerto Ricans who were awarded the Presidential Medal of Freedom.

It also includes other residents or immigrants of other ethnic heritages who have made Puerto Rico their home, and who are recognized for their life or work.

The Presidential Medal of Freedom is an award bestowed by the President of the United States and is—along with the comparable Congressional Gold Medal bestowed by an act of U.S. Congress—the highest civilian award in the United States.

It recognizes those individuals who have made "an especially meritorious contribution to the security or national interests of the United States, world peace, cultural or other significant public or private endeavors".

[1][2] Former governor Luis A. Ferré and his sister Isolina Ferré are the only pair of Puerto Rican brother and sister to have been awarded the Presidential Medal of Freedom.