The Puerto Rico Department of Labor and Human Resources (PRDLHR) (Spanish: Departamento del Trabajo y Recursos Humanos de Puerto Rico) is an executive department of the government of Puerto Rico.

The DLHR is responsible for setting and implementing public policy in the areas of labor relations, occupational safety, unemployment insurance benefits, re-employment services, and human resources training in the U.S. Commonwealth of Puerto Rico.

The Department is also responsible for some economic statistics.

It was created in 1931 but only gained formal recognition when the Constitution of the Commonwealth of Puerto Rico was approved in 1952.

The incumbent is Carlos Saavedra Gutiérrez.