Puertollano (Spanish pronunciation: [pweɾtoˈʎano]) is a municipality of Spain located in the province of Ciudad Real, Castile-La Mancha.

Puertollano is located in the Iberian Peninsula, in the transitional region between the southern half of the Inner Plateau and the northern reaches of Sierra Morena.

It lies at the natural pass linking the plains of Argamasilla to the North and the valley of the Ojailén [es] river to the south, on which a modest East–West chain of mountains interrupts,[3] at about 710 metres above sea level.

Later the region formed part of the depopulated no-mans land between Christian (Northern) Spain and the Moorish Caliphate to the south.

Nowadays the main industries are petrochemicals (Repsol), fertilisers (Fertiberia), power generation and, most recently, the manufacture of solar panels.