It connects Vieytes street of Barracas neighborhood with Bartolomé Mitre Avenue in Avellaneda Partido, crossing over Matanza River (popularly known as Riachuelo).

Some of the points to cross the river were Paso Pedro Salazar, named after a neighbor owner of a ranch near there.

The bridge was granted in concession to Gutiérrez Gálvez for a period of 5 years, including the maintenance and toll system.

The government approved the project and granted concession to Pueyrredón and his partners Mr. Medrano, Mr. Panthou and Mr. Escribano.

As a result of the disaster, Pueyrredón suffered from financial problems and died in 1870, one year before the bridge was opened to public.

The Pueyrredón bridge lasted only 13 years so it was dragged by the biggest Riachuelo flood on September 23, 1884.

In January 2009 the Pueyrredón bridge was closed to be remodelled,[7] being opened again one year later is spite of the announcements stating that works would last only 6 months.