The main street is named after St. Philomena, the Wonderworker.

It was in the beaches of Pulupandan in the early dawn of March 29, 1945 that the historical event of the landing of American liberation forces without any opposition, who together with the Filipino guerillas, drive the Japanese forces away from the island of Negros during the Battle of the Visayas.

Poverty incidence of Pulupandan Source: Philippine Statistics Authority[10][11][12][13][14][15][16][17] The current mayor of Pulupandan is Miguel C. Peña, son of its former mayor Magdaleno "Magsie" Peña who, until recently, was mayor of Moises Padilla town.

Known for being a bailiwick of the Liberal Party, the town is notable for being the only municipality in Negros Occidental where Rodrigo Duterte won during the 2016 presidential election.

Pulupandan currently has a sea port with RORO vessels traveling straight to the island province of Guimaras.