Persistent pupillary membrane (PPM) is a condition of the eye involving remnants of a fetal membrane that persist as strands of tissue crossing the pupil.

The pupillary membrane in mammals exists in the fetus as a source of blood supply for the lens.

The strands can connect to the cornea or lens, but most commonly to other parts of the iris.

Using topical atropine to dilate the pupil may help break down PPMs.

In dogs, PPM is inherited in the Basenji but can occur in other breeds such as the Pembroke Welsh Corgi, Chow Chow, Mastiff, and English Cocker Spaniel.