Her 1947 film Miss Malini, where she played the lead role, received great critical acclaim from the intelligentsia, but flopped at the box office.

[5] Later, Pushpavalli was in a relationship with actor Gemini Ganesan with whom she had two daughters, Rekha, a noted actress in Hindi film industry,[6] and Radha.

She entered the film industry as a child actress, credited as Pushpavalli Tayaramma, with a small role as young Sita in the film Sampoorna Ramayanam (8 August 1936), shot in Rajamundry in the first Studio in Andhra Region, Durga Cinitone, which was released when she was only nine years old.

Due to these preoccupations, she spent significant time on film sets, missed out on schooling and had only a rudimentary education.

Her 1947 film Miss Malini, where she played the lead role, received great critical acclaim from the intelligentsia, but flopped at the box office.

Pushpavalli next worked with Ganesan in the Tamil film Chakradhari (1948), where she was the heroine, and he played a small role.

After this point, the situation reversed; Ganesan became a huge star and Pushpavalli started getting only supporting roles, her films as heroine having mostly flopped.

The elder of them is the Bollywood actress Rekha (born in 1954) and the younger is Radha, who briefly worked in Tamil movies before marrying and moving to the United States.

As early as 1955, before the birth of Radha, Ganesan had secretly married the famous actress Savitri, and that relationship was publicly acknowledged as a valid marriage.

She gave birth to two more children, Dhanalakshmi (who later married the actor Tej Sapru) and the dancer Seshu (died 21 May 1991).