The game includes human characters modeled and named after the seven Tetrominos, which are different puzzle pieces each made of four blocks.

The Tetris style, on the other hand, has players placing shaped blocks known as Tetrominos down on the playing field.

With the exception of Swap and Fusion modes, each player can independently choose between Puyo and Tetris styles.

Swap mode has the players periodically alternate between Puyo and Tetris styles, each on its own board.

[9] Playing through each mode earns credits that can be spent in an in-game shop to unlock different art styles for Puyos and Tetriminoes and alternate voice packs.

After the power of Puyos reunites Ringo with Amitie, Arle Nadja, and Carbuncle, they are suddenly alerted by the appearance of strange blocks (Tetriminos) raining down on their world.

After managing to cure their friends of this mind control, the gang search in space to find who is responsible for the merging of the two dimensions.

With the matter solved, Tee and his crew bid farewell to Ringo and her friends as their dimensions are once again separated.

The second features Schezo going after Sig for his red hand but later rejects it after finding out it is home to his bug collection.

The third one features Ex on the SS Tetra and wonder why he is there, only to find out it is a dream of his first encounter with Tee with a bunch of unexpected guest invading it like Dark Prince and Ringo.

In February 2018, multiple games on the Steam marketplace published by Sega were given additions to their news feeds.

[11] These titles included Nights into Dreams, Tembo the Badass Elephant, Jet Set Radio, Binary Domain, and more.

PlayStation LifeStyle gave the Vita version 8/10 and called it "an example of a franchise entry done right", somewhat disliking Big Bang Mode but with high praise for Adventure and Swap.