Pyatkovo (Russian: Пятково) is a rural locality (a village) in Matigorskoye Rural Settlement of Kholmogorsky District, Arkhangelsk Oblast, Russia.

Pyatkovo is located on the Severnaya Dvina River, 39 km south of Kholmogory (the district's administrative centre) by road.

Kopachyovo is the nearest rural locality.

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