During the reign of his brother Pindale, the Prince of Pyay (Prome) led the Burmese resistance against Southern Ming and Qing incursions.
[5]: 220–223 Pye was determined to reduce the power of Yongli Emperor of Southern Ming at Sagaing and held a conference of Chinese officials.
There was a Mon rebellion around Martaban in 1661 and in 1662 Lan Na was invaded by the Siamese armies under King Narai who held the city temporarily.
The rest of his reign were largely uneventful and Pye Min died in 1672, succeeded by his son Narawara.
He was appointed governor of Prome (Pyay or Pye) on 13 September 1650 (Tuesday, 4th waning of Tawthalin 1012 ME) by King Pindale.