Pyramidellinae is a taxonomic subfamily of minute sea snails, marine gastropod mollusks in the family Pyramidellidae, the pyrams and their allies.

[2] It is one of eleven recognised subfamilies of the marine gastropod family Pyramidellidae (according to the taxonomy of Ponder & Lindberg, 1997), which are as follows: Odostomiinae, Turbonillinae, Chrysallidinae, Cingulininae, Cyclostremellinae, Sayellinae, Syrnolinae, Eulimellinae, Pyramidellinae, Odostomellinae and Tiberiinae.

In the taxonomy of Bouchet & Rocroi (2005),[3] this subfamily consists of the following tribes, adding the tribe Sayellini containing only two genera Sayella and Petitella.

According to Schander, Van Aartsen & Corgen (1999)[4] there are 12 genera within the Pyramidellinae: tribe Pyramidellini tribe Sayellini