Pyrenula inspersicollaris is a species of corticolous (bark-dwelling), crustose lichen in the family Pyrenulaceae.

[1] It is similar to the pantropical species Pyrenula septicollaris but can be distinguished by its inspersed hamathecium (a tissue layer in the ascomata containing oil droplets).

[2] The type specimen of Pyrenula inspersicollaris was collected from the southern slope of Serra de Itabaiana National Park in Areia Branca, Sergipe, Brazil, at an elevation of approximately 400 m (1,300 ft).

The ascospores are brown, irregularly biseriate (arranged in two rows), and have mostly rounded internal cavities separated from the wall by a thick layer.

Chemically, the thallus does not fluoresce under ultraviolet light, and no lichen products were detected using thin-layer chromatography.