Qal'ai Khumb (Russian: Калаихум, Tajik: Қалъаи Хумб, Qal‘a‘i Xumb/Qal'haji Xumв — meaning fortress on the banks of the river of Khumb) or Qal'a-i-Khum, also Kalai-Khumb (transliterated from Russian: Калай-Хумб), is a border town located in the Gorno-Badakhshan Autonomous Region of Tajikistan, next to the border with Afghanistan.

The town is connected by road with Afghanistan via the Tajik–Afghan Friendship Bridge.

The Saturday cross-border trade market, which was closed for several years,[5] has been reopened recently.

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