The base was established in 1967 on the site of a former French rubber plantation and was located approximately 6 km east of An Lộc in Bình Long Province.

[2]: 131 In February 1970 the 3rd Brigade, 1st Cavalry Division comprising: moved to Quản Lợi and would stay here until August 1970.

[4]: 55  On the evening of 7 April elements of the People's Army of Vietnam (PAVN/VC) 9th Division overran Quản Lợi, the 7th Regiment was ordered to destroy their heavy equipment and fall back to An Lộc.

[4]: 119 On 8 August the ARVN 18th Division launched an assault to retake Quản Lợi but were stopped by the PAVN/VC in the base's reinforced concrete bunkers.

[4]: 198  The ARVN finally attacked the PAVN/VC occupied bunkers with TOW missiles and M-202 rockets and this broke the PAVN/VC defense forcing the remaining defenders to flee the base.