The first series was originally broadcast in the United Kingdom by BBC Radio 4 in 2018, and a second in 2020.

The series has elements that pastiche Nigel Kneale's Professor Bernard Quatermass.

[1] The series follows the adventures of Professor Darius Quanderhorn, a brilliant, but crazy, scientific genius who creates fantastic devices, and has assembled a team of assistants, including his part-insect "son", a recovering amnesiac, a brilliant scientist with a half-clockwork brain, and a captured Martian hostage.

In spite of Quanderhorn saving the world many times, the British government are tired of his eccentric behaviour, and have a mole in his team.

[2] Andrew Marshall and Rob Grant also created a novel based on series one entitled "The Quanderhorn Xperimentations" and released by Gollancz Publishers.