Route 133 is a historic and heritage road of the Estrie and Montérégie regions in the province of Quebec, with north–south orientation and located on the eastern shore of the Richelieu River.

The stretch between the US border and Saint-Jean-sur-Richelieu, where Autoroute 35 begins, is relatively busy, as it provides the main link between Boston and Montreal.

Controversy persists and has gained momentum in 2005 between the Ministry of Transports of Quebec and nearly 3000 residents along the road at Saint-Denis-sur-Richelieu, Saint-Charles-sur-Richelieu, and Mont Saint-Hilaire, north of Autoroute 20.

The controversy follows the ministry's decision in 1995 to transfer north–south truck traffic from the roads parallel to the 133 and force it to converge, without an impact study, on Chemin des Patriotes, a historical and heritage path that is on a fragile and weak soil and is in the most populated area.

The resulting intense heavy traffic generates noise, vibrations, and pollution day and night, which cause health, insomnia, and safety problems in the local population.