[7][8] At the beginning of his reign, the Hittite King Suppiluliuma I reconquered Kizzuwatna, then invaded the western part of the Euphrates valley and conquered the Amurru and Nuhašše in Hanigalbat.
Suppiluliuma started to plunder the lands of the west bank of the Euphrates river and he annexed Mount Lebanon.
Suppiluliuma claims to have defeated them, but the survivors fled to the territory of Isuwa that must have been part of Tushratta's realm.
Suppiluliuma claims to have plundered the district and to have brought loot, captives, cattle, sheep and horses back to Hatti.
In a second campaign, the Hittites again crossed the Euphrates and subdued Halab, Mukish, Niya, Arahati, Apina, and Qatna as well as some cities whose names have not been preserved.
While it was common practice to incorporate enemy soldiers in the army, this might point to a Hittite attempt to counter the most potent weapon of the Mitanni, the war-chariots, by building up or strengthening their own chariot forces.
Six of the Tushratta letters, including EA 24, were subjected to Neutron Activation Analysis to match the clay composition to potential sites for Waššukanni.