[1] Originally built in 1888 to house the chief commissioners of Baluchistan during British rule, the building was damaged during the 1935 Quetta earthquake.

[6] The building's portico, made from brick, was topped by a pediment and featured two large doors on the first floor, opening onto an exposed balcony.

The founder and first governor-general of Pakistan, Muhammad Ali Jinnah, notably spent some of his last days at the Quetta Residency.

Jinnah had been advised by his physician to relocate from his Ziarat Residency to the lower altitudes of Quetta, on account of his worsening lung health.

[9] In February 1961, Queen Elizabeth II and Prince Philip, Duke of Edinburgh arrived at the Quetta Residency while visiting the city during their first royal tour of Pakistan.

[4][8] During the prime ministership of Imran Khan, the doors of Governor's House were opened for public access for the first time in October 2018.

[4] There is also a statue installed outside of Sir Hugh Shakespear Barnes, who served as the chief commissioner of Baluchistan for multiple terms in the late 19th century.

Amongst the artwork hanging inside Governor's House is an original piece of calligraphy commissioned by Sadequain in 1980 and valued at one crore rupees, gifted by the artist himself.