Quimperlé (French pronunciation: [kɛ̃pɛʁle]; Breton: Kemperle) is a commune in the Finistère department, region of Brittany, northwestern France.

The Lower Town, in the valley, is the historical centre, and developed around the Saint-Colomban church (of which only the front wall remains) and the abbey of Sainte Croix (Holy Cross).

It seems that the area was first inhabited by Neanderthals, since remains of Mousterian-style stone tools have been found in the forest between Quimperlé and Clohars-Carnoët.

A first settlement was built in the Middle Ages, called Villa Anaurot, after a 5th-century British prince, but it is thought to have been destroyed by the Normans in 868.

The church of St Michel was built in the 14th and 15th centuries and its impressive tower dominates the town from its hilltop position.