It is located on Via della Pietra Sanguigna and takes its name from the ancient Casale dei Quintiliani, which stood near the station.

Other nearby streets are Via delle Cave di Pietralata and Via del Casale Quintiliani.

It now stands in open countryside but was planned to serve the new Sistema Direzionale Orientale (SDO), which was to be sited in precisely the same area, with an interchange onto a planned 'line D' from Monte Sacro, as yet still unbuilt.

Though Line B itself opened in 1990, Quintiliani was a de facto ghost station for 13 years since trains did never stop there.

Only on 23 June 2003 the station was opened to regular service when the SDO project was dismissed.