Río Luis is a corregimiento in Santa Fé District, Veraguas Province, Panama with a population of 2,204 as of 2010.

[1] It was created by Law 58 of July 29, 1998, owing to the Declaration of Unconstitutionality of Law 1 of 1982.

[1] Its population as of 2000 was 1,708.

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