Born in Pirassununga, São Paulo, Rômulo represented União São João, Independente de Limeira and Matonense as a youth before being loaned out to Atlético Paranaense in September 2018.

[1] Back to Matonense in March 2019, he made his first team debut during the year's Campeonato Paulista Segunda Divisão before leaving the club in August for Novorizontino, after having unpaid wages.

He only started to feature regularly in the 2022 Série B, however, and renewed his contract until 2025 on 19 September 2022.

[3] Rômulo became a regular starter during the 2023 season, contributing with 11 goals and nine assists during the year.

[4] On 20 February 2024, Palmeiras announced the signing of Rômulo on a five-year contract, with the player joining the club after the 2024 Campeonato Paulista.