The Game are able to play as Roy Pulsipher or Nick Walker in a cooperative horde mode gametype against renegade ghosts also known as "deadoes", who stay on earth to avoid their fate in the afterlife.

The Game summarizes the events of the movie, covering Nick Walker's death, to his arrival at the afterlife law enforcement agency, the R.I.P.D.

The stylized comic also introduces Nick Walker's partner, Roy Pulsipher, a nineteenth-century law enforcer who also works for the R.I.P.D.

These weapons include a standard arsenal of shotguns, assault rifles, and references to the movie such as a banana or a hairdryer.

The game also provides challenges for the player to complete to earn more points at the end of a match.

The game holds an average of 39% and 42% on aggregate websites Metacritic and GameRankings.