[1] Loftin is a consultant in modeling and simulation, advanced training technologies, scientific and engineering data visualization.

He is the author or co-author of more than 100 publications and has served as principal investigator of grants and contracts totaling millions of dollars.

[4] Loftin was appointed as the vice president and CEO of Texas A&M University at Galveston in May 2005,[5] where he also held the position of professor of maritime systems engineering.

In June 2013, Loftin notified Texas A&M leadership that he would step down from the presidency in January 2014, and return to his tenured professorship.

On October 21, the Curators met behind closed doors in what was speculated by some to be related to proceedings about Loftin's role in shutting down ties between Planned Parenthood and the University.

State Rep. Caleb Jones, R-Columbia, speculated on Twitter that Loftin would be fired for his role in shutting down MU's connections to Planned Parenthood.

Citing Loftin's handling of race and cultural issues, the firing of the dean of the School of Medicine, the abrupt cancellation of graduate student health insurance subsidies in August, and the elimination of the vice chancellor for health sciences, they wrote that Loftin had created a “toxic environment through threat, fear and intimidation."