The R561 is a Regional Route in South Africa.

[1] Its northern origin is Zanzibar border post with Botswana in Limpopo province.

It heads south, crossing the R572 at the village of Maasstroom.

It crosses the N11 at a staggered crossing at the village of Baltimore and ends at an intersection with the R518 at Marken.

This South African road or road transport-related article is a stub.