RCD Espanyol was one of the pioneering teams in women's football in Spain, playing its first match as early as 1970.

Espanyol had its worst-ever finish in the league when they ended the 2019–20 season in 16th place, winning none of their 21 matches and losing 16.

[7] That season, Espanyol were relegated to the Reto Iberdrola for the first time in their history, finishing 16th out of 18 in the league table.

[8] They failed to be promoted back immediately on the final matchday of the 2021–22 season, losing 3–0 to fellow Catalan club Levante Las Planas, who took the title instead.

[9] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.